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A NEW BASE-STABLE LINKER FOR SOLID-PHASE OLIGONUCLEOTIDE SYNTHESIS

Abstract:
The succinyl-sarcosyl linker (1b), which is stable to prolonged contact with 1,8-diazabicyclo[5.4.0]undec-7-ene but cleaves rapidly with aqueous ammonia, is of potential value in solid-phase oligonucleotide synthesis.
Publication status:
Published

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Publisher copy:
10.1039/c39890000891

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Institution:
University of Oxford
Division:
MPLS
Department:
Chemistry
Sub department:
Organic Chemistry
Role:
Author
Journal:
JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS
Issue:
14
Pages:
891-893
Publication date:
1989-07-15
DOI:
ISSN:
0022-4936
Language:
English
Pubs id:
pubs:400324
UUID:
uuid:3af5c171-3a21-48c1-81d8-8d5f27da91b2
Local pid:
pubs:400324
Source identifiers:
400324
Deposit date:
2013-11-16

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