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Benchmarking stable isotope labeling based quantitative proteomics.

Abstract:

Several quantitative mass spectrometry based technologies have recently evolved to interrogate the complexity, interconnectivity and dynamic nature of proteomes. Currently, the most popular methods use either metabolic or chemical isotope labeling with MS based quantification or chemical labeling using isobaric tags with MS/MS based quantification. Here, we assess the performance of three of the most popular approaches through systematic independent large scale quantitative proteomics experim...

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Publication status:
Published

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Publisher copy:
10.1016/j.jprot.2012.10.009

Authors


Altelaar, AF More by this author
Preisinger, C More by this author
Hennrich, ML More by this author
Schram, AW More by this author
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Journal:
Journal of proteomics
Volume:
88
Pages:
14-26
Publication date:
2013-08-05
DOI:
EISSN:
1876-7737
ISSN:
1874-3919
URN:
uuid:3adf561d-e56c-40fe-bf12-00c2b3657442
Source identifiers:
384546
Local pid:
pubs:384546

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