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Salmonella Typhi and Salmonella Paratyphi A elaborate distinct systemic metabolite signatures during enteric fever

Abstract:

The host–pathogen interactions induced by Salmonella Typhi and Salmonella Paratyphi A during enteric fever are poorly understood. This knowledge gap, and the human restricted nature of these bacteria, limit our understanding of the disease and impede the development of new diagnostic approaches. To investigate metabolite signals associated with enteric fever we performed two dimensional gas chromatography with time-of-flight mass spectrometry (GCxGC/TOFMS) on plasma from patients with S. Typh...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.7554/eLife.03100.001

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Publisher:
eLife Sciences Publications Publisher's website
Journal:
eLife Journal website
Volume:
2014
Issue:
3
Article number:
e03100
Publication date:
2014-07-01
Acceptance date:
2014-05-26
DOI:
EISSN:
2050-084X
Source identifiers:
476820
Language:
English
Keywords:
UUID:
uuid:3a35aa0a-8be0-4c34-95f9-df272e8d40f0
Local pid:
pubs:476820
Deposit date:
2014-08-06

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