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Structure and association of ATP-binding cassette transporter nucleotide-binding domains

Abstract:

ATP-binding cassette transporters are responsible for the uptake and efflux of a multitude of substances across both eukaryotic and prokaryotic membranes. Members of this family of proteins are involved in diverse physiological processes including antigen presentation, drug efflux from cancer cells, bacterial nutrient uptake and cystic fibrosis. In order to understand more completely the role of these multidomain transporters an integrated approach combining structural, pharmacological and bi...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/S0304-4157(01)00008-9

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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM Clinical Laboratory Sciences
Role:
Author
Publisher:
Elsevier
Journal:
Biochimica et Biophysica Acta (BBA) - Biomembranes Journal website
Volume:
1561
Issue:
1
Pages:
47–64
Publication date:
2002-03-01
DOI:
ISSN:
0006-291X
Language:
English
Keywords:
Subjects:
UUID:
uuid:3a23b5d9-5b37-41cb-b24a-7de4222bd848
Local pid:
ora:8094
Deposit date:
2014-02-25

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