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METHYL 5-O-TERT-BUTYLDIPHENYLSILYL-2-DEOXY-ALPHA,BETA-D-THREO-PENTOFURANOSIDE AS A DIVERGENT INTERMEDIATE FOR THE SYNTHESIS OF 3'-SUBSTITUTED-2',3'-DIDEOXYNUCLEOSIDES - SYNTHESIS OF 3'-AZIDO-3'-DEOXYTHYMIDINE, 3'-DEOXY-3'-FLUOROTHYMIDINE AND 3'-CYANO-3'-DEOXYTHYMIDINE

Abstract:: The use of methyl 5-0-tert-butyldiphenylsilyl-2-deoxy-α, β -D-threo-pentofuranoside, prepared from D-xylose,as a divergent intermediate for the synthesis of 3'-substituted-2',3'-dideoxynucleosides is illustrated by its conversion into 3'-azido-3'-deoxythymidine, 3'-deoxy-3'-fluorothymidine and 3'-cyano-3'-deoxythymidine. © 1988.

Publication status:: Published

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APA Style

Fleet, G., Son, J., & Derome, A. (1988). METHYL 5-O-TERT-BUTYLDIPHENYLSILYL-2-DEOXY-ALPHA,BETA-D-THREO-PENTOFURANOSIDE AS A DIVERGENT INTERMEDIATE FOR THE SYNTHESIS OF 3'-SUBSTITUTED-2',3'-DIDEOXYNUCLEOSIDES - SYNTHESIS OF 3'-AZIDO-3'-DEOXYTHYMIDINE, 3'-DEOXY-3'-FLUOROTHYMIDINE AND 3'-CYANO-3'-DEOXYTHYMIDINE. TETRAHEDRON, 44(2), 625–636.

MLA Style

Fleet, G., et al. “METHYL 5-O-TERT-BUTYLDIPHENYLSILYL-2-DEOXY-ALPHA,BETA-D-THREO-PENTOFURANOSIDE AS A DIVERGENT INTERMEDIATE FOR THE SYNTHESIS OF 3'-SUBSTITUTED-2',3'-DIDEOXYNUCLEOSIDES - SYNTHESIS OF 3'-AZIDO-3'-DEOXYTHYMIDINE, 3'-DEOXY-3'-FLUOROTHYMIDINE AND 3'-CYANO-3'-DEOXYTHYMIDINE.” TETRAHEDRON, vol. 44, no. 2, 1988, pp. 625–36.

Chicago Style

Fleet, G, J Son, and A Derome. 1988. “METHYL 5-O-TERT-BUTYLDIPHENYLSILYL-2-DEOXY-ALPHA,BETA-D-THREO-PENTOFURANOSIDE AS A DIVERGENT INTERMEDIATE FOR THE SYNTHESIS OF 3'-SUBSTITUTED-2',3'-DIDEOXYNUCLEOSIDES - SYNTHESIS OF 3'-AZIDO-3'-DEOXYTHYMIDINE, 3'-DEOXY-3'-FLUOROTHYMIDINE AND 3'-CYANO-3'-DEOXYTHYMIDINE.” TETRAHEDRON 44 (2): 625–36.
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Publisher copy:: 10.1016/S0040-4020(01)85850-6

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+ Fleet, G More by this author

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+ Son, J More by this author

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+ Derome, A More by this author

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Bibliographic Details

Journal:: TETRAHEDRON
Volume:: 44
Issue:: 2
Pages:: 625-636
Publication date:: 1988-01-01
DOI:: 10.1016/S0040-4020(01)85850-6
ISSN:: 0040-4020

Item Description

Language:: English
Pubs id:: pubs:42934
UUID:: uuid:39bc4f1e-c0ee-4ef5-ad19-c015f239ad94
Local pid:: pubs:42934
Source identifiers:: 42934
Deposit date:: 2012-12-19

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Copyright date:: 1988

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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