Reducing suffering in experimental autoimmune encephalomyelitis (EAE).

Journal article

This report is based on discussions and submissions from an expert working group consisting of veterinarians, animal care staff and scientists with expert knowledge relevant to the field. It aims to facilitate the implementation of the Three Rs (replacement, reduction and refinement) in the use of animal models or procedures involving experimental autoimmune encephalomyelitis (EAE), an experimental model used in multiple sclerosis research. The emphasis is on refinement since this has the gre...

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Authors: Wolfensohn, S; Hawkins, P; Lilley, E; Anthony, D; Chambers, C

• Publication status: Published
• Journal: Journal of pharmacological and toxicological methods
• Volume: 67
• Issue: 3
• Pages: 169-176
• Publication date: 2013-01-01
• DOI: 10.1016/j.vascn.2013.01.009
• EISSN: 1873-488X
• ISSN: 1056-8719
• Language: English
• Keywords: Stress, Psychological; Veterinarians; Multiple Sclerosis; Rats; Disease Models, Animal; Animals; Encephalomyelitis, Autoimmune, Experimental; Animal Welfare; Research; Animal Husbandry; Mice