- Abstract:
-
A series of seven monoclonal antibodies was produced against the T-lineage-specific 50 kd T11 sheep erythrocyte rosette (SRBC) receptor protein in order to define the function of the molecule. Three distinct epitopes were detected: T11(1), the SRBC binding site expressed on all T lymphocytes and thymocytes; T11(2), an epitope unrelated to the SRBC binding site but with a similar distribution; and T11(3), a neo-epitope expressed only upon T-cell activation. Simultaneous triggering of T11(2) an...
Expand abstract - Publication status:
- Published
- Publisher copy:
- 10.1016/0092-8674(84)90039-4
-
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- Journal:
- Cell
- Volume:
- 36
- Issue:
- 4
- Pages:
- 897-906
- Publication date:
- 1984-04-05
- DOI:
- EISSN:
-
1097-4172
- ISSN:
-
0092-8674
- URN:
-
uuid:397a142d-7ed3-4375-b734-04128fad632a
- Source identifiers:
-
19893
- Local pid:
- pubs:19893
- Copyright date:
- 1984
Journal article
An alternative pathway of T-cell activation: a functional role for the 50 kd T11 sheep erythrocyte receptor protein.
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