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Automated virtual reality cognitive therapy versus virtual reality mental relaxation therapy for the treatment of persistent persecutory delusions in patients with psychosis (THRIVE): a parallel-group, single-blind, randomised controlled trial in England with mediation analyses

Abstract:

Background: Persecutory delusions are a major psychiatric problem that often do not respond sufficiently to standard pharmacological or psychological treatments. We developed a new brief automated virtual reality (VR) cognitive treatment that has the potential to be used easily in clinical services. We aimed to compare VR cognitive therapy with an alternative VR therapy (mental relaxation), with an emphasis on understanding potential mechanisms of action.

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/S2215-0366(23)00257-2

Authors


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Institution:
University of Oxford
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Experimental Psychology
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Experimental Psychology
Role:
Author
ORCID:
0000-0002-2749-1386
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Primary Care Health Sciences
Role:
Author
ORCID:
0000-0002-3401-9637
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Primary Care Health Sciences
Role:
Author
ORCID:
0000-0003-0331-7364


Publisher:
Elsevier
Journal:
Lancet Psychiatry More from this journal
Volume:
10
Issue:
11
Pages:
836-847
Publication date:
2023-09-21
Acceptance date:
2023-07-14
DOI:
EISSN:
2215-0374
ISSN:
2215-0366


Language:
English
Keywords:
Pubs id:
1492595
Local pid:
pubs:1492595
Deposit date:
2023-07-15

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