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The Rogan-Gladen estimator for outcome misclassification

Abstract:

Outcome measurement error is common in epidemiologic studies and often leads to bias in estimates of prevalences, risks, and their contrasts. The Rogan-Gladen estimator (1) provides an elegant solution to account for misclassification of a binary outcome when estimating risk or prevalence, which, in turn, can be used to produce valid estimates of contrasts in these measures. Here, we review the Rogan-Gladen estimator, provide intuition for its properties, and briefly illustrate how it can be combined with approaches to account for other sources of bias.

Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1093/aje/kwag057

Authors

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Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Sub department:
Clinical Trial Service Unit
Role:
Author
ORCID:
0000-0001-9506-4047


Publisher:
Oxford University Press
Journal:
American Journal of Epidemiology More from this journal
Article number:
kwag057
Publication date:
2026-03-30
Acceptance date:
2026-03-05
DOI:
EISSN:
1476-6256
ISSN:
0002-9262


Language:
English
Pubs id:
2388649
Local pid:
pubs:2388649
Deposit date:
2026-03-12
ARK identifier:

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