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New insights into HIV-1 specific cytotoxic T-lymphocyte responses in exposed, persistently seronegative Kenyan sex workers.

Abstract:

A clearer understanding of HIV-1 specific immune responses in highly-exposed, persistently seronegative (HEPS) subjects is important in developing models of HIV-1 protective immunity. HIV-1 specific cytotoxic T-lymphocytes (CTL) have been described in a cohort of HEPS Kenyan sex workers, and recent work has further elucidated these responses. CTL specific for HIV-1 Env were found in the blood of over half the sex workers meeting criteria for HIV resistance, and in some women recognized unmapp...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Experimental Medicine Division,
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Institution:
University of Oxford
Department:
Oxford, MSD, RDM, Molecular Medicine
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Volume:
79
Issue:
1-2
Pages:
3-13
Publication date:
2001-11-05
DOI:
EISSN:
1879-0542
ISSN:
0165-2478
URN:
uuid:396adf7f-0978-4ae8-acb6-f098571ea944
Source identifiers:
26260
Local pid:
pubs:26260

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