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A cool hybrid approach to the herpesvirus 'life' cycle.

Abstract:

Electron cryo tomography (cryoET) is an ideal technique to study virus-host interactions at molecular resolution. Imaging of biological specimens in a frozen-hydrated state assures a close to native environment. Various virus-host cell interactions have been analysed in this way, with the herpesvirus 'life' cycle being the most comprehensively studied. The data obtained were further integrated with fluorescence and soft X-ray cryo microscopy data applied on experimental systems covering a wid...

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Publication status:
Published

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Publisher:
Elsevier
Journal:
Current opinion in virology
Volume:
5
Issue:
1
Pages:
42-49
Publication date:
2014-04-01
DOI:
EISSN:
1879-6265
ISSN:
1879-6257
Language:
English
Keywords:
Pubs id:
pubs:449204
UUID:
uuid:392f32dd-98d2-4c83-b597-c1b36a70dab8
Local pid:
pubs:449204
Source identifiers:
449204
Deposit date:
2014-07-05

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