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A quantitative trait locus influencing anxiety in the laboratory rat.

Abstract:

A critical test for a gene that influences susceptibility to fear in animals is that it should have a consistent pattern of effects across a broad range of conditioned and unconditioned models of anxiety. Despite many years of research, definitive evidence that genetic effects operate in this way is lacking. The limited behavioral test regimes so far used in genetic mapping experiments and the lack of suitable multivariate methodologies have made it impossible to determine whether the quantit...

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Publication status:
Published

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Publisher copy:
10.1101/gr.203402

Authors


Fernández-Teruel, A More by this author
Escorihuela, RM More by this author
Aguilar, R More by this author
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Journal:
Genome research
Volume:
12
Issue:
4
Pages:
618-626
Publication date:
2002-04-05
DOI:
EISSN:
1549-5469
ISSN:
1088-9051
URN:
uuid:38f1ad16-0fd7-4c13-9fab-2f6d845f887b
Source identifiers:
29153
Local pid:
pubs:29153

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