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Antibodies to Plasmodium falciparum and Plasmodium vivax merozoite surface protein 5 in Indonesia: species-specific and cross-reactive responses.

Abstract:

BACKGROUND: Merozoite surface protein (MSP) 5 is a candidate antigen for a malaria vaccine. In cross-sectional and longitudinal studies, we measured MSP5 antibody responses in Papuans with acute Plasmodium falciparum malaria, Plasmodium vivax malaria, and mixed P. falciparum and P. vivax malaria and in those with past exposure. METHODS: Enzyme-linked immunosorbant assay (ELISA) was used to quantitate antibody responses to P. falciparum MSP5 (PfMSP5) and P. vivax MSP5 (PvMSP5) in 82 subjects ...

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Publication status:
Published

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Publisher copy:
10.1086/588711

Authors


Woodberry, T More by this author
Hanley, JC More by this author
de Silva, HD More by this author
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Journal:
The Journal of infectious diseases
Volume:
198
Issue:
1
Pages:
134-142
Publication date:
2008-07-05
DOI:
EISSN:
1537-6613
ISSN:
0022-1899
URN:
uuid:38f0e3e6-9acd-4a96-80ed-88dc86bd0d23
Source identifiers:
61501
Local pid:
pubs:61501

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