Journal article icon

Journal article

ASYMMETRIC-SYNTHESIS OF ANTI-ALPHA-ALKYL-BETA-AMINO ACIDS

Abstract:

An investigation into the asymmetric induction accompanying alkylations of enolates derived from the highly diastereoselective conjugate addition of lithium (R)-N-benzyl-N-α-methylbenzylamide (R)-1 to crotonate and cinnamate esters has been performed. The access to different enolate geometries afforded by the conjugate addition process and subsequent enolate regeneration by deprotonation of the β-amino ester conjugate adducts enabled two disparate sets of selectivity data to be compiled. Alth...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1039/p19940001129

Authors


More by this author
Institution:
University of Oxford
Department:
Oxford, MPLS, Chemistry, Organic Chemistry
Role:
Author
Journal:
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1
Volume:
9
Issue:
9
Pages:
1129-1139
Publication date:
1994-05-07
DOI:
EISSN:
1364-5463
ISSN:
0300-922X
URN:
uuid:38f014bb-792d-49a0-b746-5f034631ea0a
Source identifiers:
168604
Local pid:
pubs:168604

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP