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Mortality in HIV infection is independently predicted by host iron status and SLC11A1 and HP genotypes, with new evidence of a gene-nutrient interaction.

Abstract:

BACKGROUND: Iron-related genes and iron status may independently contribute to variable HIV outcomes. The nature of the biologically plausible gene-nutrient interaction remains unknown. OBJECTIVES: The objectives were to investigate whether iron-related genotypes and clinically abnormal iron status independently predict mortality in HIV and whether a gene-nutrient interaction exists. DESIGN: Baseline plasma, DNA, and clinical data were obtained from 1362 HIV-seropositive Gambian adults follow...

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Publication status:
Published

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Publisher copy:
10.3945/ajcn.2009.27709

Authors


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Journal:
American journal of clinical nutrition
Volume:
90
Issue:
1
Pages:
225-233
Publication date:
2009-07-01
DOI:
EISSN:
1938-3207
ISSN:
0002-9165
Source identifiers:
41234
Language:
English
Keywords:
Pubs id:
pubs:41234
UUID:
uuid:38c1ef08-618e-4870-9947-26edcc3ab77d
Local pid:
pubs:41234
Deposit date:
2012-12-19

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