Journal article
DNA charge neutralization by linear polymers: irreversible binding.
- Abstract:
-
We develop a deterministic mathematical model to describe the way in which polymers bind to DNA by considering the dynamics of the gap distribution that forms when polymers bind to a DNA plasmid. In so doing, we generalize existing theory to account for overlaps and binding cooperativity whereby the polymer binding rate depends on the size of the overlap. The proposed mean-field models are then solved using a combination of numerical and asymptotic methods. We find that overlaps lead to highe...
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- Publication status:
- Published
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- Publisher copy:
- 10.1103/physreve.74.011904
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Authors
Bibliographic Details
- Journal:
- Physical review. E, Statistical, nonlinear, and soft matter physics
- Volume:
- 74
- Issue:
- 1 Pt 1
- Pages:
- 011904
- Publication date:
- 2006-07-01
- DOI:
- EISSN:
-
1550-2376
- ISSN:
-
1539-3755
- Source identifiers:
-
319101
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:319101
- UUID:
-
uuid:38acb995-8a2c-418c-9207-ce71de581d37
- Local pid:
- pubs:319101
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2006
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