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Neurobiological evidence for attention bias to food, emotional dysregulation, disinhibition and deficient somatosensory awareness in obesity with binge eating disorder

Abstract:

Objectives: To refine the biobehavioral markers of binge eating disorder (BED). Methods: We conducted fMRI brain scans using images of high energy processed food (HEPF), low energy unprocessed food (LEUF), or non-foods (NF) in 42 adults (obese with BED [obese -BED; n = 13] and obese with no BED [obese non-BED; n = 29]) selected via ads. Two blood oxygenated level dependent (BOLD) signal contrast maps were examined: food versus nonfood, and HEPF versus LEUF. In addition, score differences...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted Manuscript

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Publisher copy:
10.1016/j.physbeh.2017.11.003

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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Primary Care; Primary Care Health Sciences
Role:
Author
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Grant:
RO1DK07406 (AG) and RO1DK080153 (AG
Publisher:
Elsevier Publisher's website
Journal:
Physiology and Behavior Journal website
Volume:
184
Pages:
122-128
Publication date:
2017-11-08
Acceptance date:
2017-11-05
DOI:
ISSN:
0031-9384
Pubs id:
pubs:743550
URN:
uri:3866bd25-e00e-4946-8551-9e24c5986a26
UUID:
uuid:3866bd25-e00e-4946-8551-9e24c5986a26
Local pid:
pubs:743550

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