Journal article
Use of a selective inhibitor to define the chemotherapeutic potential of the plasmodial hexose transporter in different stages of the parasite's life cycle.
- Abstract:
-
During blood infection, malarial parasites use D-glucose as their main energy source. The Plasmodium falciparum hexose transporter (PfHT), which mediates the uptake of D-glucose into parasites, is essential for survival of asexual blood-stage parasites. Recently, genetic studies in the rodent malaria model, Plasmodium berghei, found that the orthologous hexose transporter (PbHT) is expressed throughout the parasite's development within the mosquito vector, in addition to being essential durin...
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- Publisher copy:
- 10.1128/aac.01739-10
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Bibliographic Details
- Journal:
- Antimicrobial agents and chemotherapy
- Volume:
- 55
- Issue:
- 6
- Pages:
- 2824-2830
- Publication date:
- 2011-06-01
- DOI:
- EISSN:
-
1098-6596
- ISSN:
-
0066-4804
- Source identifiers:
-
268263
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:268263
- UUID:
-
uuid:38586cc1-7303-41ac-b048-3cb460349a7d
- Local pid:
- pubs:268263
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2011
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