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Analysis of a Budding Yeast Cell Cycle Model Using the Shapes of Local Sensitivity Functions

Abstract:

The Chen et al. (Mol Biol Cell 2000, 11, 369-391) budding yeast cell cycle model is a biochemical kinetic model that describes how the controlling protein concentrations change during a proliferation cycle. Time dependence of local sensitivity coefficients was calculated for all variables and parameters of the model. Some of the local sensitivity coefficients - time functions could also be obtained from another one by multiplying it with a constant, which means that these functions exhibit gl...

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Publication status:
Published

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Publisher copy:
10.1002/kin.20366

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Volume:
40
Issue:
11
Pages:
710-720
Host title:
INTERNATIONAL JOURNAL OF CHEMICAL KINETICS
Publication date:
2008-11-01
DOI:
EISSN:
1097-4601
ISSN:
0538-8066
Source identifiers:
100611
Pubs id:
pubs:100611
UUID:
uuid:3837c38f-9554-49b1-866c-14d4404e235d
Local pid:
pubs:100611
Deposit date:
2012-12-19

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