Journal article
Susceptibility to sequelae of human ocular chlamydial infection associated with allelic variation in IL10 cis-regulation.
- Abstract:
-
Trachoma, an infectious disease of the conjunctiva caused by Chlamydia trachomatis, causes scarring and blindness in some infected individuals but not others. In an African community where trachoma is endemic, we have previously identified an IL10 haplotype that is associated with increased risk of scarring complications. Here we examine the hypothesis that the risk haplotype (H-RISK) affects levels of IL10 expression in the conjunctiva during active trachoma infection. To overcome potential ...
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- Publication status:
- Published
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- Publisher copy:
- 10.1093/hmg/ddm310
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Authors
Bibliographic Details
- Journal:
- Human molecular genetics
- Volume:
- 17
- Issue:
- 2
- Pages:
- 323-329
- Publication date:
- 2008-01-01
- DOI:
- EISSN:
-
1460-2083
- ISSN:
-
0964-6906
- Source identifiers:
-
40627
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:40627
- UUID:
-
uuid:382fd568-3414-46a5-bcc6-72a921ed2df2
- Local pid:
- pubs:40627
- Deposit date:
- 2012-12-19
Terms of use
- Copyright date:
- 2008
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