Journal article
Design, recruitment, and microbiological considerations in human challenge studies.
- Abstract:
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Since the 18th century a wealth of knowledge regarding infectious disease pathogenesis, prevention, and treatment has been accumulated from findings of infection challenges in human beings. Partly because of improvements to ethical and regulatory guidance, human challenge studies-involving the deliberate exposure of participants to infectious substances-have had a resurgence in popularity in the past few years, in particular for the assessment of vaccines. To provide an overview of the potent...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Accepted manuscript, 488.0KB)
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- Publisher copy:
- 10.1016/s1473-3099(15)00068-7
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Authors
Funding
Jenner Institute
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Wellcome Trust
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British Society for Immunology
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Bibliographic Details
- Publisher:
- Elsevier Publisher's website
- Journal:
- Lancet. Infectious diseases Journal website
- Volume:
- 15
- Issue:
- 7
- Pages:
- 840-851
- Publication date:
- 2015-07-01
- DOI:
- EISSN:
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1474-4457
- ISSN:
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1473-3099
- Source identifiers:
-
525607
Item Description
- Language:
- English
- Keywords:
- Pubs id:
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pubs:525607
- UUID:
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uuid:380b1f68-2b68-42a1-83d0-a896f083ed08
- Local pid:
- pubs:525607
- Deposit date:
- 2015-11-28
Terms of use
- Copyright holder:
- Elsevier Ltd
- Copyright date:
- 2015
- Notes:
- Copyright © 2015 Elsevier Ltd. This manuscript version is made available under the CC-BY-NC-ND 4.0 license
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