Journal article
The major transition state in folding need not involve the immobilization of side chains.
- Abstract:
-
During protein folding in which few, if any, definable kinetic intermediates are observable, the nature of the transition state is central to understanding the course of the reaction. Current experimental data does not distinguish the relative contributions of side chain immobilization and dehydration phenomena to the major rate-limiting transition state whereas this distinction is central to theoretical models that attempt to simulate the behavior of proteins during folding. Renaturation of ...
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- Publication status:
- Published
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- Publisher copy:
- 10.1073/pnas.97.11.5790
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Bibliographic Details
- Journal:
- Proceedings of the National Academy of Sciences of the United States of America
- Volume:
- 97
- Issue:
- 11
- Pages:
- 5790-5795
- Publication date:
- 2000-05-01
- DOI:
- EISSN:
-
1091-6490
- ISSN:
-
0027-8424
- Source identifiers:
-
224867
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:224867
- UUID:
-
uuid:37e5672d-1e97-47b8-84eb-8b11379dbb86
- Local pid:
- pubs:224867
- Deposit date:
- 2013-11-16
Terms of use
- Copyright date:
- 2000
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