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Interneuron development is disrupted in preterm brains with diffuse white matter injury: observations in mouse and human

Abstract:

Preterm brain injury, occurring in approximately 30% of infants born <32 weeks gestational age, is associated with an increased risk of neurodevelopmental disorders, such as autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD). The mechanism of gray matter injury in preterm born children is unclear and likely to be multifactorial; however, inflammation, a high predictor of poor outcome in preterm infants, has been associated with disrupted interneuron maturation ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.3389/fphys.2019.00955

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Role:
Author
ORCID:
0000-0001-7828-673X
Medical Research Council More from this funder
Publisher:
Frontiers Media Publisher's website
Journal:
Frontiers in Physiology Journal website
Volume:
10
Article number:
955
Publication date:
2019-07-30
Acceptance date:
2019-07-09
DOI:
EISSN:
1664-042X
Pmid:
31417418
Language:
English
Keywords:
Pubs id:
1040529
Local pid:
pubs:1040529
Deposit date:
2021-09-21

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