Journal article
Deuterium-reinforced polyunsaturated fatty acids protect against atherosclerosis by lowering lipid peroxidation and hypercholesterolemia
- Abstract:
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Background and aims Oxidative modification of lipoproteins is a crucial step in atherosclerosis development. Isotopic-reinforced polyunsaturated fatty acids (D-PUFAs) are more resistant to reactive oxygen species-initiated chain reaction of lipid peroxidation than regular hydrogenated (H-)PUFAs. We aimed at investigating the effect of D-PUFA treatment on lipid peroxidation, hypercholesterolemia and atherosclerosis development. Methods Transgenic APOE*3-Leiden.CETP mice, a well-established ...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Accepted manuscript, pdf, 1.8MB)
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- Publisher copy:
- 10.1016/j.atherosclerosis.2017.06.916
Authors
Bibliographic Details
- Publisher:
- Elsevier Publisher's website
- Journal:
- Atherosclerosis Journal website
- Volume:
- 264
- Pages:
- 100-107
- Publication date:
- 2017-06-21
- Acceptance date:
- 2017-06-20
- DOI:
- ISSN:
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0021-9150
Item Description
- Keywords:
- Pubs id:
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pubs:702205
- UUID:
-
uuid:378458c5-65e0-4891-bb60-cc458455b81b
- Local pid:
- pubs:702205
- Source identifiers:
-
702205
- Deposit date:
- 2017-06-29
Terms of use
- Copyright holder:
- Elsevier BV
- Copyright date:
- 2017
- Notes:
- Copyright © 2017 Elsevier B.V. This is the accepted manuscript version of the article. The final version is available online from Elsevier at: https://doi.org/10.1016/j.atherosclerosis.2017.06.916
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