Journal article
Science and bioethics of CRISPR-Cas9 gene editing: An analysis towards separating facts and fiction .
- Abstract:
-
Since its emergence in 2012, the genome editing technique known as CRISPR-Cas9 and its scientific use have rapidly expanded globally within a very short period of time. The technique consists of using an RNA guide molecule to bind to complementary DNA sequences, which simultaneously recruits the endonuclease Cas9 to introduce double-stranded breaks in the target DNA. The resulting double-stranded break is then repaired, allowing modification or removal of specific DNA bases. The technique has...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Bibliographic Details
- Publisher:
- Yale School of Medicine Publisher's website
- Journal:
- Yale Journal of Biology and Medicine Journal website
- Volume:
- 90
- Issue:
- 4
- Pages:
- 625-634
- Publication date:
- 2017-12-19
- EISSN:
-
1551-4056
- ISSN:
-
0044-0086
- Pmid:
-
29259526
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:813168
- UUID:
-
uuid:377b67ec-61e6-444d-afa7-d5f133529797
- Local pid:
- pubs:813168
- Source identifiers:
-
813168
- Deposit date:
- 2018-01-23
Terms of use
- Copyright holder:
- ©2017, Yale Journal of Biology and Medicine
- Copyright date:
- 2017
- Notes:
- This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives License, which permits for noncommercial use, distribution, and reproduction in any digital medium, provided the original work is properly cited and is not altered in any way
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