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A yeast artificial chromosome containing the mouse homeobox cluster Hox-2.

Abstract:

We have isolated two genes, Hox-2.8 and Hox-2.9, from the mouse homeobox cluster Hox-2, located on chromosome 11. A 120-kilobase yeast artificial chromosome (YAC) containing a large region of the murine Hox-2 cluster, including 45 kilobases of sequence upstream of the most 5' gene, was cloned. The DNA sequence of the YAC is unrearranged relative to the genomic map. We have subcloned from the YAC insert a homeobox gene, Hox-2.8, whose homeodolmain is highly related to that of the Drosophila ho...

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Publication status:
Published

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Publisher copy:
10.1073/pnas.87.12.4751

Authors


Rubock, MJ More by this author
Papalopulu, N More by this author
Krumlauf, R More by this author
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Journal:
Proceedings of the National Academy of Sciences of the United States of America
Volume:
87
Issue:
12
Pages:
4751-4755
Publication date:
1990-06-05
DOI:
EISSN:
1091-6490
ISSN:
0027-8424
URN:
uuid:376ca936-f6a6-4aef-8f5f-2e5d67472117
Source identifiers:
53527
Local pid:
pubs:53527

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