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A continuum model of cell proliferation and nutrient transport in a perfusion bioreactor.

Abstract:

Tissue engineering aims to regenerate, repair or replace organs or defective tissues. This tissue regeneration often occurs in a bioreactor. Important challenges in tissue engineering include ensuring adequate nutrient supply, maintaining the desired cell distribution and achieving sufficiently high cell yield. To put laboratory experiments into a theoretical framework, mathematical modelling of the physical and biochemical processes involved in tissue growth is a useful tool. In this work, w...

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Publication status:
Published

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Publisher copy:
10.1093/imammb/dqr022

Authors


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Institution:
University of Oxford
Division:
MPLS
Department:
Mathematical Institute
Role:
Author
Journal:
Mathematical medicine and biology : a journal of the IMA
Volume:
30
Issue:
1
Pages:
21-44
Publication date:
2013-03-01
DOI:
EISSN:
1477-8602
ISSN:
1477-8599
Source identifiers:
394098
Language:
English
Keywords:
Pubs id:
pubs:394098
UUID:
uuid:37490be8-35b7-4f7c-9174-c9d0f0a354d1
Local pid:
pubs:394098
Deposit date:
2013-11-16

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