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The Groningen hypothermic liver perfusion pump: functional evaluation of a new machine perfusion system.

Abstract:

To improve preservation of donor livers, we have developed a portable hypothermic machine perfusion (HMP) system as an alternative for static cold storage. A prototype of the system was built and evaluated on functionality. Evaluation criteria included 24 h of adequate pressure controlled perfusion, sufficient oxygenation, a maintained 0-4 degrees C temperature and sterile conditions. Porcine livers were perfused with pump pressures that were set at 4 mmHg (continuous, portal vein) and 30/20 ...

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Publication status:
Published

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Publisher copy:
10.1007/s10439-006-9207-4

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Journal:
Annals of biomedical engineering
Volume:
34
Issue:
12
Pages:
1924-1934
Publication date:
2006-12-01
DOI:
EISSN:
1573-9686
ISSN:
0090-6964
Source identifiers:
190967
Language:
English
Keywords:
Pubs id:
pubs:190967
UUID:
uuid:373c3e4c-71f8-4f06-952b-09f765460e05
Local pid:
pubs:190967
Deposit date:
2012-12-19

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