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N-terminal Pro-B-type natriuretic peptide, vascular disease risk, and cholesterol reduction among 20,536 patients in the MRC/BHF heart protection study.

Abstract:

OBJECTIVES: We sought to assess the ability of N-terminal pro-B-type natriuretic peptide (N-BNP) to predict vascular events in high-risk people and to test whether statins benefit people with high levels of N-BNP.

BACKGROUND: The predictive value of N-BNP for occlusive vascular events and the effects of statins in people with high N-BNP levels are uncertain.

METHODS: A total of 20,536 people were assigned randomly to simvasta...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.jacc.2006.08.052

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Sub department:
Clinical Trial Service Unit
Role:
Author
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Medical Research Council More from this funder
British Heart Foundation More from this funder
Merck and Co. More from this funder
Roche Vitamins Ltd. More from this funder
Publisher:
Elsevier Publisher's website
Journal:
Journal of the American College of Cardiology Journal website
Volume:
49
Issue:
3
Pages:
311-319
Publication date:
2007-01-01
DOI:
EISSN:
1558-3597
ISSN:
0735-1097
Source identifiers:
33731

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