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Journal article

Regulation of actin nucleation and autophagosome formation.

Abstract:

Autophagy is a process of self-eating, whereby cytosolic constituents are enclosed by a double-membrane vesicle before delivery to the lysosome for degradation. This is an important process which allows for recycling of nutrients and cellular components and thus plays a critical role in normal cellular homeostasis as well as cell survival during stresses such as starvation or hypoxia. A large number of proteins regulate various stages of autophagy in a complex and still incompletely understoo...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1007/s00018-016-2224-z

Authors


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Role:
Author
ORCID:
0000-0002-5005-1864
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Institution:
University of Oxford
Division:
MSD
Department:
Oncology
Oxford college:
Linacre College
Role:
Author
Publisher:
Springer Publisher's website
Journal:
Cellular and Molecular Life Sciences Journal website
Volume:
73
Issue:
17
Pages:
3249-3263
Publication date:
2016-05-01
Acceptance date:
2016-04-08
DOI:
EISSN:
1420-9071
ISSN:
1420-682X
Pmid:
27147468
Source identifiers:
619933
Language:
English
Keywords:
Pubs id:
pubs:619933
UUID:
uuid:36dcfb69-701a-420e-a727-cf1311056ab9
Local pid:
pubs:619933
Deposit date:
2018-03-09

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