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A vaccine against serogroup B Neisseria meningitidis: Dealing with uncertainty

Abstract:

Neisseria meningitidis is an important cause of invasive bacterial infection in children worldwide. Although serogroup C meningococcal disease has all but disappeared in the past decade as a direct result of immunisation programmes in Europe, Canada, and Australia, meningitis and septicaemia caused by serogroup B meningococci remain uncontrolled. A vaccine (4CMenB) has now been licensed for use in the European Union, comprising three immunogenic antigens (identified with use of reverse vaccin...

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Authors


Andrews, SM More by this author
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Institution:
University of Oxford
Department:
Oxford, MSD, Paediatrics, Biomedical Research Centre
Publisher:
Lancet Publishing Group
Journal:
The Lancet Infectious Diseases
Volume:
14
Issue:
5
Pages:
426-434
Publication date:
2014
DOI:
EISSN:
1474-4457
ISSN:
1473-3099
URN:
uuid:36bcb8f9-3527-402e-918f-bd83af2b26af
Source identifiers:
464285
Local pid:
pubs:464285
Language:
English

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