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A randomised trial of granulocyte-macrophage colony-stimulating factor for neonatal sepsis: outcomes at 2 years.

Abstract:

OBJECTIVE: The authors performed a randomised trial in very preterm small-for-gestational age (SGA) babies to determine if prophylaxis with granulocyte-macrophage colony-stimulating factor (GM-CSF) improves outcomes (the PROGRAMS trial). Despite increased neutrophil counts following GM-CSF, the authors reported no significant difference in neonatal sepsis-free survival. PATIENTS AND METHODS: 280 babies born <31 weeks of gestation and SGA were entered into the trial. Outcome was determined...

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Publication status:
Published

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Journal:
Archives of disease in childhood. Fetal and neonatal edition
Volume:
98
Issue:
1
Pages:
F46-F53
Publication date:
2013-01-01
DOI:
EISSN:
1468-2052
ISSN:
1359-2998
Source identifiers:
329099
Language:
English
Keywords:
Pubs id:
pubs:329099
UUID:
uuid:3692d55d-d6fd-4910-9663-72790620a051
Local pid:
pubs:329099
Deposit date:
2013-11-16

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