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A biologist's guide to Bayesian phylogenetic analysis

Abstract:
Bayesian methods have become very popular in molecular phylogenetics due to the availability of user-friendly software implementing sophisticated models of evolution. However, Bayesian phylogenetic models are complex, and analyses are often carried out using default settings, which may not be appropriate. Here, we summarize the major features of Bayesian phylogenetic inference and discuss Bayesian computation using Markov chain Monte Carlo (MCMC), the diagnosis of an MCMC run, and ways of summarising the MCMC sample. We discuss the specification of the prior, the choice of the substitution model, and partitioning of the data. Finally, we provide a list of common Bayesian phylogenetic software and provide recommendations as to their use.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1038/s41559-017-0280-x

Authors


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Institution:
University of Oxford
Division:
MPLS
Department:
Zoology
Role:
Author


Publisher:
Nature Publishing Group
Journal:
Nature Ecology and Evolution More from this journal
Volume:
1
Issue:
2017
Pages:
1446-1454
Publication date:
2017-09-21
Acceptance date:
2017-07-17
DOI:
ISSN:
2397-334X


Pubs id:
pubs:809763
UUID:
uuid:3681d271-ddd3-4051-a749-cccf7a7bcb44
Local pid:
pubs:809763
Source identifiers:
809763
Deposit date:
2017-12-07

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