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The striosome and matrix compartments of the striatum: a path through the labyrinth from neurochemistry towards function

Abstract:

The striatum is a heterogeneous structure with a diverse range of neuron types and neuromodulators. Three decades of anatomical and biochemical studies have established that the neurochemical organization of striatum is not uniformly heterogeneous, but rather, can be differentiated into neurochemically discrete compartments known as striosomes (also known as patches) and matrix. These compartments are well understood to differ in their expression of neurochemical markers, with some difference...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1021/acschemneuro.6b00333

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Department:
Oxford, MSD, Physiology Anatomy and Genetics
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Department:
Oxford, MSD, Physiology Anatomy and Genetics
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Funding agency for:
Brimblecombe, K
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Funding agency for:
Brimblecombe, K
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Funding agency for:
Cragg, SJ
Publisher:
American Chemical Society Publisher's website
Journal:
ACS Chemical Neuroscience Journal website
Volume:
8
Issue:
2
Pages:
235–242
Publication date:
2016-12-01
Acceptance date:
2016-12-01
DOI:
ISSN:
1948-7193
Pubs id:
pubs:663680
URN:
uri:364f80ff-7f17-48e5-8028-739f5c578a56
UUID:
uuid:364f80ff-7f17-48e5-8028-739f5c578a56
Local pid:
pubs:663680

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