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The striosome and matrix compartments of the striatum: a path through the labyrinth from neurochemistry towards function

Abstract:

The striatum is a heterogeneous structure with a diverse range of neuron types and neuromodulators. Three decades of anatomical and biochemical studies have established that the neurochemical organization of striatum is not uniformly heterogeneous, but rather, can be differentiated into neurochemically discrete compartments known as striosomes (also known as patches) and matrix. These compartments are well understood to differ in their expression of neurochemical markers, with some difference...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1021/acschemneuro.6b00333

Authors

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Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Author
More from this funder
Funding agency for:
Brimblecombe, K
Cragg, S
Grant:
H-1003
MR/K013866/1
More from this funder
Funding agency for:
Brimblecombe, K
Cragg, S
Grant:
H-1003
MR/K013866/1
Publisher:
American Chemical Society
Journal:
ACS Chemical Neuroscience More from this journal
Volume:
8
Issue:
2
Pages:
235–242
Publication date:
2016-12-01
Acceptance date:
2016-12-01
DOI:
ISSN:
1948-7193
Keywords:
Pubs id:
pubs:663680
UUID:
uuid:364f80ff-7f17-48e5-8028-739f5c578a56
Local pid:
pubs:663680
Source identifiers:
663680
Deposit date:
2016-12-02

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