Journal article
Increased Expression of Phosphorylated FADD in Anaplastic Large Cell and Other T-Cell Lymphomas.
- Abstract:
-
FAS-associated protein with death domain (FADD) is a major adaptor protein involved in extrinsic apoptosis, embryogenesis, and lymphocyte homeostasis. Although abnormalities of the FADD/death receptor apoptotic pathways have been established in tumorigenesis, fewer studies have analyzed the expression and role of phosphorylated FADD (pFADD). Our identification of FADD as a lymphoma-associated autoantigen in T-cell lymphoma patients raises the possibility that pFADD, with its correlation with ...
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Bibliographic Details
- Publisher:
- Libertas Academica Ltd.
- Journal:
- Biomarker insights
- Volume:
- 9
- Pages:
- 77-84
- Publication date:
- 2014-01-01
- DOI:
- EISSN:
-
1177-2719
- ISSN:
-
1177-2719
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- Copyright date:
- 2014
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