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Increased Expression of Phosphorylated FADD in Anaplastic Large Cell and Other T-Cell Lymphomas.

Abstract:

FAS-associated protein with death domain (FADD) is a major adaptor protein involved in extrinsic apoptosis, embryogenesis, and lymphocyte homeostasis. Although abnormalities of the FADD/death receptor apoptotic pathways have been established in tumorigenesis, fewer studies have analyzed the expression and role of phosphorylated FADD (pFADD). Our identification of FADD as a lymphoma-associated autoantigen in T-cell lymphoma patients raises the possibility that pFADD, with its correlation with ...

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Publisher copy:
10.4137/bmi.s16553

Authors


Publisher:
Libertas Academica Ltd.
Journal:
Biomarker insights
Volume:
9
Pages:
77-84
Publication date:
2014-01-01
DOI:
EISSN:
1177-2719
ISSN:
1177-2719
Language:
English
Keywords:
Pubs id:
pubs:486863
UUID:
uuid:363e9b92-bc8c-4938-bd46-0a084020d691
Local pid:
pubs:486863
Source identifiers:
486863
Deposit date:
2014-10-17

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