Journal article icon

Journal article

Regulation of elongating RNA polymerase II by forkhead transcription factors in yeast.

Abstract:

The elongation phase of transcription by RNA polymerase II (RNAPII) is highly regulated and tightly linked to pre-messenger RNA (pre-mRNA) processing. Recent studies have implicated an early elongation checkpoint that facilitates the link to pre-mRNA processing. Here we show that the yeast forkhead transcription factors, Fkh1p and Fkh2p, associate with the coding regions of active genes and influence, in opposing ways, transcriptional elongation and termination. These events are coordinated w...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1126/science.1081379

Authors


Journal:
Science (New York, N.Y.)
Volume:
300
Issue:
5618
Pages:
492-495
Publication date:
2003-04-05
DOI:
EISSN:
1095-9203
ISSN:
0036-8075
URN:
uuid:3639bb57-0dc0-4ff7-b56c-f321d47bf4ac
Source identifiers:
101184
Local pid:
pubs:101184

Terms of use


Metrics


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP