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First-line HIV treatment failures in non-B subtypes and recombinants: a cross-sectional analysis of multiple populations in Uganda

Abstract:

BACKGROUND: Our understanding of HIV-1 and antiretroviral treatment (ART) is strongly biased towards subtype B, the predominant subtype in North America and western Europe. Efforts to characterize the response to first-line treatments in other HIV-1 subtypes have been hindered by the availability of large study cohorts in resource-limited settings. To maximize our statistical power, we combined HIV-1 sequence and clinical data from every available study population associated with the Join...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's Version

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Publisher copy:
10.1186/s12981-019-0218-2

Authors


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ORCID:
0000-0003-3779-154X
Ndashimye, E More by this author
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Grant:
R56 AI049170
P30 AI036219
R01 AI049170
R21 AI071747
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Grant:
BOP-149562
FRN-130609
PJT-155990
PJT-156178
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Publisher:
BioMed Central Publisher's website
Journal:
AIDS Research and Therapy Journal website
Volume:
16
Issue:
1
Pages:
Article: 3
Publication date:
2019-01-22
Acceptance date:
2019-01-08
DOI:
ISSN:
1742-6405
Pubs id:
pubs:971362
URN:
uri:36285fb2-7740-48a4-8aa8-2b9c7e3a432f
UUID:
uuid:36285fb2-7740-48a4-8aa8-2b9c7e3a432f
Local pid:
pubs:971362

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