Journal article
Prevalence and risk factors for active convulsive epilepsy in Kintampo, Ghana
- Abstract:
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Introduction:
Epilepsy is common in sub-Saharan Africa, but there is little data in West Africa, to develop public health measures for epilepsy in this region.
Methods:We conducted a three-stage cross-sectional survey to determine the prevalence and risk factors for active convulsive epilepsy (ACE), and estimated the treatment gap in Kintampo situated in the middle of Ghana.
Results:249 people with ACE were identified in a study population of 113,796 individuals. After adjusting for attrition and the sensitivity of the screening method, the prevalence of ACE was 10.1/1000 (95% Confidence Interval (95%CI) 9.5-10.7). In children aged <18 years, risk factors for ACE were: family history of seizures (OR=3.31; 95%CI: 1.83-5.96), abnormal delivery (OR=2.99; 95%CI: 1.07-8.34), problems after birth (OR=3.51; 95%CI: 1.02-12.06), and exposure to Onchocerca volvulus (OR=2.32; 95%CI: 1.12-4.78). In adults, a family history of seizures (OR=1.83; 95%CI: 1.05-3.20), never attended school (OR=11.68; 95%CI: 4.80-28.40), cassava consumption (OR=3.92; 95%CI: 1.14-13.54), pork consumption (OR=1.68; 95%CI: 1.09-2.58), history of snoring at least 3 nights per week (OR=3.40: 95%CI: 1.56-7.41), exposure to Toxoplasma gondii (OR=1.99; 95%CI: 1.15-3.45) and Onchocerca volvulus (OR=2.09: 95%CI: 1.29-3.40) were significant risk factors for the development of ACE. The self-reported treatment gap was 86.9% (95%CI: 83.5%-90.3%).
Conclusion:ACE is common within the middle belt of Ghana and could be reduced with improved obstetric care and prevention of parasite infestations such as Onchocerca volvulus and Toxoplasma gondii.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Preview, Version of record, pdf, 179.7KB, Terms of use)
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- Publisher copy:
- 10.11604/pamj.2015.21.29.6084
Authors
- Funder identifier:
- https://ror.org/03x94j517
- Grant:
- MR/K012126/1
- Publisher:
- Pan African Medical Journal
- Journal:
- Pan African Medical Journal More from this journal
- Volume:
- 21
- Article number:
- 29
- Place of publication:
- Uganda
- Publication date:
- 2015-05-13
- Acceptance date:
- 2015-04-22
- DOI:
- ISSN:
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1937-8688
- Pmid:
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26401223
- Language:
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English
- Keywords:
- Pubs id:
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586265
- Local pid:
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pubs:586265
- Deposit date:
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2024-11-23
Terms of use
- Copyright holder:
- Ae-Ngibise et al
- Copyright date:
- 2015
- Rights statement:
- ©2015 Kenneth Ayuurebobi Ae-Ngibise et al. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
- Licence:
- CC Attribution (CC BY)
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