A SARS-Cov-2 sensor based on upconversion nanoparticles and graphene oxide

Journal article

Since the beginning of the COVID-19 pandemic, there has been an increased need for the development of novel diagnostic solutions that can accurately and rapidly detect SARS-CoV-2 infection. In this work, we demonstrate the targeting of viral oligonucleotide markers within minutes without the requirement of a polymerase chain reaction (PCR) amplification step via the use of oligonucleotide-coated upconversion nanoparticles (UCNPs) and graphene oxide (GO).

Authors: Alexaki, K; Kyriazi, ME; Greening, J; Taemaitree, L; El-Sagheer, AH

• Publication status: Published
• Peer review status: Peer reviewed
• Publisher: Royal Society of Chemistry
• Journal: RSC Advances
• Volume: 12
• Issue: 29
• Pages: 18445-18449
• Publication date: 2022-06-22
• DOI: 10.1039/d2ra03599e
• EISSN: 2046-2069
• ISSN: 2046-2069
• Language: English
• Keywords: Coronavirus disease 2019 (COVID-19); Oxide; Metallurgy; Optoelectronics; Graphene; Doping; Nanotechnology; Medicine; Virology; 2019-20 coronavirus outbreak; Nanoparticle; Materials science; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Photon upconversion