Journal article
Mindful diagnostics in culture-negative endocarditis: early noninvasive diagnosis of Tropheryma whipplei by plasma microbial cell-free DNA
- Abstract:
- Tropheryma whipplei was identified by plasma microbial cell-free DNA sequencing within 4 days in severe culture-negative endocarditis after antibiotics had already been started. The result supported earlier diagnostic clarification and antimicrobial de-escalation before valve pathology was available, illustrating a practical diagnostic-stewardship role for noninvasive sequencing in high-acuity endocarditis.
- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Preview, Version of record, pdf, 390.9KB, Terms of use)
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- Publisher copy:
- 10.1017/ash.2026.10416
Authors
- Publisher:
- Cambridge University Press
- Journal:
- Antimicrobial Stewardship & Healthcare Epidemiology More from this journal
- Volume:
- 6
- Issue:
- 1
- Article number:
- e179
- Publication date:
- 2026-06-16
- Acceptance date:
- 2026-04-28
- DOI:
- EISSN:
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2732-494X
- ISSN:
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2732-494X
- Language:
-
English
- Source identifiers:
-
4235514
- Deposit date:
-
2026-06-16
- ARK identifier:
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Terms of use
- Copyright date:
- 2026
- Licence:
- CC Attribution (CC BY)
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