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Journal article

The immunological synapse and the actin cytoskeleton: molecular hardware for T cell signaling.

Abstract:
The actin cytoskeleton seems to play two critical roles in the activation of T cells. One of these roles is T cell shape development and movement, including formation of the immunological synapse. The other is the formation of a scaffold for signaling components. This review focuses on the recent convergence of cell biology and immunology studies to explain the role of the actin cytoskeleton in creating the molecular basis for immunological synapse formation and T cell signaling.

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Publisher copy:
10.1038/76877

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Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Role:
Author
Journal:
Nature immunology
Volume:
1
Issue:
1
Pages:
23-29
Publication date:
2000-07-01
DOI:
EISSN:
1529-2916
ISSN:
1529-2908
Source identifiers:
482663
Language:
English
Keywords:
Pubs id:
pubs:482663
UUID:
uuid:35bc1ce8-b5e9-4854-a604-828f9a88586d
Local pid:
pubs:482663
Deposit date:
2014-09-14

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