Journal article
Neurite dispersion: A new marker of multiple sclerosis spinal cord pathology?
- Abstract:
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Objective: Conventional magnetic resonance imaging (MRI) of the multiple sclerosis spinal cord is limited by low specificity regarding the underlying pathological processes, and new MRI metrics assessing microscopic damage are required. We aim to show for the first time that neurite orientation dispersion (i.e., variability in axon/dendrite orientations) is a new biomarker that uncovers previously undetected layers of complexity of multiple sclerosis spinal cord pathology. Also, we validat...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Files:
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(Preview, Version of record, pdf, 1.8MB, Terms of use)
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- Publisher copy:
- 10.1002/acn3.445
Authors
Funding
+ European Research Council
More from this funder
Funding agency for:
Alexander, D
Grant:
666992-2
634541
+ Multiple Sclerosis Society
More from this funder
Funding agency for:
Yiannakas, M
Grant:
G0601617
892/08
+ Engineering and Physical Sciences Research Council
More from this funder
Funding agency for:
Grussu, F
Ianuş, A
Alexander, D
Grant:
EP/M020533/1
M507970
666992-2
Bibliographic Details
- Publisher:
- Wiley
- Journal:
- Annals of Clinical and Translational Neurology More from this journal
- Volume:
- 4
- Issue:
- 9
- Pages:
- 663-679
- Publication date:
- 2017-08-15
- Acceptance date:
- 2017-07-12
- DOI:
- ISSN:
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2328-9503
Item Description
- Keywords:
- Pubs id:
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pubs:724633
- UUID:
-
uuid:35ae631f-b7a3-4ba3-8da7-b5edfa2bbcc7
- Local pid:
-
pubs:724633
- Source identifiers:
-
724633
- Deposit date:
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2017-09-03
Terms of use
- Copyright holder:
- © 2017 Grussu, et al
- Copyright date:
- 2017
- Notes:
- This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
- Licence:
- CC Attribution (CC BY)
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