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Single-cell twitching chemotaxis in developing biofilms

Abstract:

Bacteria form surface-attached communities, known as biofilms, which are central to bacterial biology and how they affect us. While surface attached bacteria often experience strong chemical gradients, it remains unclear whether single cells can effectively perform chemotaxis on surfaces. Here we use microfluidic chemical gradients and massively-parallel automated tracking to study the behavior of the pathogen Pseudomonas aeruginosa during early biofilm development. We show that individual ce...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Accepted manuscript

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Publisher copy:
10.1073/pnas.1600760113

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Institution:
University of Oxford
Department:
Oxford, MPLS, Zoology
More by this author
Institution:
University of Oxford
Department:
Oxford, MPLS, Zoology
More by this author
Institution:
University of Oxford
Department:
Oxford, MPLS, Zoology
Publisher:
National Academy of Sciences Publisher's website
Journal:
Proceedings of the National Academy of Sciences Journal website
Publication date:
2016-05-24
DOI:
ISSN:
1091-6490
URN:
uuid:35971a57-28ba-4b60-8ca3-df7ee29071e8
Source identifiers:
620292
Local pid:
pubs:620292

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