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GRADE guidelines: 7. Rating the quality of evidence--inconsistency.

Abstract:

This article deals with inconsistency of relative (rather than absolute) treatment effects in binary/dichotomous outcomes. A body of evidence is not rated up in quality if studies yield consistent results, but may be rated down in quality if inconsistent. Criteria for evaluating consistency include similarity of point estimates, extent of overlap of confidence intervals, and statistical criteria including tests of heterogeneity and I(2). To explore heterogeneity, systematic review authors sho...

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Authors


Guyatt, GH More by this author
Woodcock, J More by this author
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Journal:
Journal of clinical epidemiology
Volume:
64
Issue:
12
Pages:
1294-1302
Publication date:
2011-12-05
DOI:
EISSN:
1878-5921
ISSN:
0895-4356
URN:
uuid:35491730-936f-412c-ba90-2350e3177527
Source identifiers:
215686
Local pid:
pubs:215686

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