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cAMP signalling meets mitochondrial compartments.

Abstract:

Mitochondria are highly dynamic organelles comprising at least three distinct areas, the OMM (outer mitochondrial membrane), the IMS (intermembrane space) and the mitochondrial matrix. Physical compartmentalization allows these organelles to host different functional domains and therefore participate in a variety of important cellular actions such as ATP synthesis and programmed cell death. In a surprising homology, it is now widely accepted that the ubiquitous second messenger cAMP uses the ...

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Publication status:
Published

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Publisher copy:
10.1042/bst20130281

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Institution:
University of Oxford
Department:
Oxford, MSD, Physiology Anatomy and Genetics
Publisher:
Portland Press Ltd
Journal:
Biochemical Society transactions
Volume:
42
Issue:
2
Pages:
265-269
Publication date:
2014-04-05
DOI:
EISSN:
1470-8752
ISSN:
0300-5127
URN:
uuid:34f0f715-91d5-43ae-b77a-c1f82071a0a5
Source identifiers:
459021
Local pid:
pubs:459021

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