Journal article

Fluorous synthesis of 18F radiotracers with the [18F]fluoride ion: nucleophilic fluorination as the detagging process.

Abstract:: Tag team: The flouro-detagging of flourous sulfonates by the [ 18F]fluoride ion was found to be an advantageous strategy for the preparation of various 18F-labeled prosthetic groups and known radiotracers (see picture). Fluorous solid phase extraction (FSPE) was used to separate the excess fluorous precursor from the labeled material, which suggests that traditional purification protocols such as distillation or tedious separation can be avoided. (Chemical Equation Presented). © 2009 Wiley-VCH Verlag GmbH and Co. KGaA.

Publication status:: Published

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APA Style

Bejot, R., Fowler, T., Carroll, L., Boldon, S., Moore, J., Declerck, J., & Gouverneur, V. (2009). Fluorous synthesis of 18F radiotracers with the [18F]fluoride ion: nucleophilic fluorination as the detagging process. Angewandte Chemie (International Ed. in English), 48(3), 586–589.

MLA Style

Bejot, R., et al. “Fluorous Synthesis of 18F Radiotracers with the [18F]Fluoride Ion: Nucleophilic Fluorination as the Detagging Process.” Angewandte Chemie (International Ed. in English), vol. 48, no. 3, 2009, pp. 586–89.

Chicago Style

Bejot, R, T Fowler, L Carroll, S Boldon, J Moore, J Declerck, and V Gouverneur. 2009. “Fluorous Synthesis of 18F Radiotracers with the [18F]Fluoride Ion: Nucleophilic Fluorination as the Detagging Process.” Angewandte Chemie (International Ed. in English) 48 (3): 586–89.
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Publisher copy:: 10.1002/anie.200803897

Authors

+ Bejot, R More by this author

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+ Fowler, T More by this author

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+ Carroll, L More by this author

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+ Boldon, S More by this author

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+ Moore, J More by this author

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Journal:: Angewandte Chemie (International ed. in English) More from this journal
Volume:: 48
Issue:: 3
Pages:: 586-589
Publication date:: 2009-01-01
DOI:: 10.1002/anie.200803897
EISSN:: 1521-3773
ISSN:: 1433-7851

Language:: English
Keywords:: Ions

Fluorine Compounds

Fluorine Radioisotopes

Halogenation

Molecular Structure
Pubs id:: pubs:34502
UUID:: uuid:34b2edb4-f26d-43dc-9de4-cca16a32f0eb
Local pid:: pubs:34502
Source identifiers:: 34502
Deposit date:: 2012-12-19

Terms of use

Copyright date:: 2009

Licence:: Terms and Conditions of Use for Oxford University Research Archive

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