- Abstract:
-
Acquisition of non-sterilizing natural immunity to Plasmodium falciparum malaria has been shown in low transmission areas following multiple exposures. However, conflicting data from endemic areas suggest that the parasite may interfere with the induction of effective B-cell responses. To date, the impact of blood-stage parasite exposure on antigen-specific B cells has not been reported following controlled human malaria infection (CHMI). Here we analysed human B-cell responses in a series of...
Expand abstract - Publication status:
- Published
- Peer review status:
- Peer reviewed
- Version:
- Publisher's version
- Files:
-
-
(pdf, 601.6KB)
-
- Publisher copy:
- 10.1111/imm.12226
-
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- Publisher:
- Wiley Publisher's website
- Journal:
- Immunology Journal website
- Volume:
- 141
- Issue:
- 4
- Pages:
- 628-644
- Publication date:
- 2014-04-05
- DOI:
- EISSN:
-
1365-2567
- ISSN:
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0019-2805
- URN:
-
uuid:349a3527-c655-4871-940a-833d93710948
- Source identifiers:
-
441719
- Local pid:
- pubs:441719
- Language:
- English
- Keywords:
- Copyright holder:
- Elias et al.
- Copyright date:
- 2014
- Notes:
-
Copyright © 2013 The Authors. Immunology published by John Wiley and Sons Ltd.
This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
Journal article
Analysis of human B-cell responses following ChAd63-MVA MSP1 and AMA1 immunization and controlled malaria infection.
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European Malaria Vaccine Development Association
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European Commission
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National Institute of Health Research
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