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A coding polymorphism in matrix metalloproteinase 9 reduces risk of scarring sequelae of ocular Chlamydia trachomatisinfection

Abstract:

Background: Trachoma, an infectious disease of the conjunctiva caused by Chlamydia trachomatis, is an important global cause of blindness. A dysregulated extracellular matrix (ECM) proteolysis during the processes of tissue repair following infection and inflammation are thought to play a key role in the development of fibrotic sequelae of infection, which ultimately leads to blindness. Expression and activity of matrix metalloproteinase 9 (MMP-9), a ma...

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Publication status:
Published
Peer review status:
Peer reviewed
Version:
Publisher's version

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Publisher copy:
10.1186/1471-2350-7-40

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Publisher:
BioMed Central Publisher's website
Journal:
BMC Medical Genetics Journal website
Volume:
7
Pages:
Article: 40
Publication date:
2006-04-27
Acceptance date:
2006-04-27
DOI:
EISSN:
1471-2350
URN:
uuid:3489790a-2ae2-4815-9c9b-7008c841df65
Source identifiers:
40014
Local pid:
pubs:40014

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