Inconsistency between direct and indirect comparisons of competing interventions: meta-epidemiological study.

Journal article

OBJECTIVE: To investigate the agreement between direct and indirect comparisons of competing healthcare interventions. DESIGN: Meta-epidemiological study based on sample of meta-analyses of randomised controlled trials. Data sources Cochrane Database of Systematic Reviews and PubMed. Inclusion criteria Systematic reviews that provided sufficient data for both direct comparison and independent indirect comparisons of two interventions on the basis of a common comparator and in which the odds r...

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Authors: Song, F; Xiong, T; Parekh-Bhurke, S; Loke, Y; Sutton, A

• Publication status: Published
• Journal: BMJ (Clinical research ed.)
• Volume: 343
• Issue: 7821
• Pages: d4909
• Publication date: 2011-01-01
• DOI: 10.1136/bmj.d4909
• EISSN: 1756-1833
• ISSN: 0959-8138
• Language: English
• Keywords: Bias (Epidemiology); Review Literature as Topic; Humans; Epidemiologic Studies; Randomized Controlled Trials as Topic; Intervention Studies; Reproducibility of Results; Meta-Analysis as Topic; Comparative Effectiveness Research; Research Design; Treatment Outcome