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Plasmodium falciparum: the behavior of clinical isolates in an in vitro model of infected red blood cell sequestration.

Abstract:

An in vitro model of Plasmodium falciparum-infected red blood cell sequestration which uses C32 amelanotic melanoma cells as targets has been used to examine the binding capacity of infected red blood cells from subjects with naturally acquired P. falciparum infections of varying severity. The binding of infected red blood cells (IRBCs) to melanoma cells was specific to cells containing mature parasites. Variations in target cell density and in conditions of growth had significant effects on ...

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Publication status:
Published

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Institution:
University of Oxford
Department:
Oxford, MSD, Clinical Medicine, Tropical Medicine
Whittle, HC More by this author
Greenwood, BM More by this author
Journal:
Experimental parasitology
Volume:
65
Issue:
2
Pages:
202-208
Publication date:
1988-04-05
DOI:
EISSN:
1090-2449
ISSN:
0014-4894
URN:
uuid:34796849-dcee-4124-8913-7397b2090d7a
Source identifiers:
184974
Local pid:
pubs:184974

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